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Osteoarthritis is the most prevalent form of degenerative joint disease and source of disability among adults in the US, affecting approximately 23% of the adult population. The condition can occur in any joint, but most often affects the hands and weight-bearing joints, such as the knee, hip, and facet of the spine.

As we age, chronic injuries and normal wear and tear cause the articular cartilage that cushions the joint to wear down. Friction from bones rubbing against each other causes pain and inflammation, in turn leading to further degeneration of tissue. Articular cartilage covering the bones has a limited capacity to repair that reduces as we age. Without treatment, deterioration will progress.


How to manage arthritis naturally without medication or surgery


Platelet Rich Plasma Therapy condenses the many types of cells contained in the patient's blood to inject directly into damaged tissue. Platelet cells contain growth factors, such as alpha-granules, and tissue building proteins central to tissue repair. They also stimulate release of localized stem cells. By condensing platelet cells, their healing capacity is magnified to greatly enhance the cellular environment to accelerate and enhance the healing process.

Stem Cell Therapy uses mesenchymal stem cells derived from the patient’s own tissue, generally from bone marrow or adipose (fat) tissue. These cells have the capacity to differentiate into various cell types that compose the joint- cartilage, tendon, muscle, and bones. Through a process called "signaling," their key role is to direct other cells through the healing process. Arthritis can overwhelm the body's ability to regenerate tissue by depleting localized stem cells. Harvested cells are injected directly into damaged tissue to supply what the body needs for more effective healing.

Osteopathic Manipulative Medicine focuses on improving joint restriction and misalignment. When bones in the joint do not fit together as designed, several things happen. Bones can rub together causing irritation and subsequent inflammation. Structural dysfunction can also cause strain on surrounding ligaments and tendons, creating further damage, pain, and inflammation. Osteopathic manipulation helps to restore the structural integrity of the joint, allowing it to function naturally and effectively. Osteopathic Manipulation will release muscle tension around the affected joint and improve range of motion. OMT will also help to ensure function of related areas to more evenly distribute movement and loading on the joints.


Traditional Treatment vs Orthobiologic Procedures

Traditional treatment for arthritis has focused on treating the inflammation and pain associated with this condition. Although pain relievers can make you feel better, they do not change the course of the disease. Some treatments can actually make your condition worse. Cortisone will reduce inflammation, but in turn inhibits healing and further damages tissue. Surgery, on the other hand, ignores the body's ability to heal from within and removes the tissue itself, causing lengthy rehabilitation and often poor results.

Orthobiologic procedures treat the root cause of your pain using cells from your own body to provide long lasting results. The focus is regeneration of cartilage cells to heal from within as your body does naturally, only with a little help from a concentration of your cells. Research showing how the body actually heals on a molecular level has allowed physicians to develop more effective ways to treat arthritis. Regenerative Orthopedics is radically changing the way musculoskeletal conditions are treated, providing cures for people who have been living — until now — with few treatment options.                 Read more about Arthritis and PRP


Medical research focusing on how our body actually heals on a cellular level is

providing new options for treatment of osteoarthritis.


Regenexx is a world-wide network of select, highly skilled physicians who are specially trained in interventional procedures for orthopedic conditions. Regenexx provides the world's most advanced, research-driven, regenerative orthopedic procedures in North America, Europe, the Middle East, Asia and Australia. Specializing in advanced non-surgical procedures for joint Injuries, osteoarthritis, and other orthopedic conditions, Dr. Minotti brings these procedures to you!

PRP video

Platelet Rich Plasma Therapy successfully treats injured joints and osteoarthritis. Blood drawn from the patient is condensed and re-injected to enhance the natural healing process.

To determine if Regenerative Orthopedics will be helpful for you, please tell us about your condition.

View live results from Regenexx registry.


Leader in orthobiologic treatment for musculoskeletal conditions

Dr. Dennis E. Minotti II, DO

Dr. Minotti is specialty trained in Neuromusculoskeletal Medicine by the American Board of Neuromusculoskeletal Medicine with advanced training in Regenerative Medicine. His primary focus is Regenerative Orthopedics, nonsurgical procedures designed to accelerate regeneration of cells in healing of acute and chronic musculoskeletal injuries. Founder of North Texas Musculoskeletal Medicine in Southlake TX, Dr. Minotti is a pioneer in the field of regenerative medicine.

He believes that orthobiologic procedures such as Platelet Rich Plasma (PRP) and Stem Cell Therapy are a new frontier in medicine, offering treatments that effectively bridge the gap between medications that mask pain and invasive surgery. As scientists learn more about the physiology of how our bodies heal, healthcare is able to use this research to find new and better treatments.


Many scientists believe the concept of intrinsic healing is a new frontier. Medicine is changing. The wonders of the human body and its ability to balance and heal itself are at the center of this medical renaissance.


We Can Help

To learn more about what we can do to help you, please call our office at 817-416-0970. We will thoroughly diagnose your condition and present you with treatment options. From there we will guide you along your road to recovery.



Renaissance means rebirth or regeneration. Every few generations medicine takes a major turn. We’re at one of those junctures now with regenerative medicine — where healing is triggered from within the human body. It’s bringing a whole new universe to how physicians provide care. It’s a whole new realm of healing. --Mayo Clinic Center for Regenerative Medicine